Infliximab treatment for refractory Kawasaki disease with coronary artery aneurysm.

نویسندگان

  • Taku Oishi
  • Mikiya Fujieda
  • Taisuke Shiraishi
  • Miki Ono
  • Kazuo Inoue
  • Akiyoshi Takahashi
  • Hideo Ogura
  • Hiroshi Wakiguchi
چکیده

Tumor necrosis factor-alpha (TNF-alpha) is considered to be 1 of the factors that induce vasculitis, including coronary artery aneurysm (CA), in Kawasaki disease (KD), because the blood concentration of TNF-alpha is higher in patients with CA compared with those without. Therefore, an anti-TNF-alphaagent (infliximab) was administered to a 1-month-old girl with refractory KD complicated by CA and subsequently, the CA improved and KD was controlled without complications 20 months after the onset.

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عنوان ژورنال:
  • Circulation journal : official journal of the Japanese Circulation Society

دوره 72 5  شماره 

صفحات  -

تاریخ انتشار 2008